<p>Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort</p>
نویسندگان
چکیده
منابع مشابه
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
BACKGROUND Chronic mucus hypersecretion (CMH) is associated with an increased frequency of respiratory infections, excess lung function decline, and increased hospitalisation and mortality rates in the general population. It is associated with smoking, but it is unknown why only a minority of smokers develops CMH. A plausible explanation for this phenomenon is a predisposing genetic constitutio...
متن کاملRhinovirus infection induces mucus hypersecretion.
Rhinorrhea is a prominent symptom of the common cold. Although increases in vascular permeability and serous cell secretion have been demonstrated in human nasal mucus during active rhinovirus infections, changes in mucin constituents have not been quantified. Nonallergic ( n= 48) and asymptomatic allergic rhinitis ( n = 32) subjects were inoculated with rhinovirus type hanks before the spring ...
متن کاملRevisited role for mucus hypersecretion in the pathogenesis of COPD.
Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disease of which the basic pathophysiological mechanisms remain largely unknown. On the basis of recent results from pathological studies and large clinical trials, the presence of airway inflammation does not seem to be sufficient to explain the complexity of the disease and the relatively poor response to treatment. I...
متن کاملDissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.
Smoking is a notorious risk factor for chronic mucus hypersecretion (CMH). CMH frequently occurs in chronic obstructive pulmonary disease (COPD). The question arises whether the same single-nucleotide polymorphisms (SNPs) are related to CMH in smokers with and without COPD. We performed two genome-wide association studies of CMH under an additive genetic model in male heavy smokers (≥20 pack-ye...
متن کاملthe effect of using critical discourse analytical tools on the improvement of the learners level of critical thinking in reading comprehension
?it is of utmost priority for an experienced teacher to train the mind of the students, and enable them to think critically and correctly. the most important question here is that how to develop such a crucial ability? this study examines a new way to the development of critical thinking utilizing critical discourse analytical tools. to attain this goal, two classes of senior english la...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2020
ISSN: 1178-2005
DOI: 10.2147/copd.s267002